Selected Publications - Professor Ian T. Young



Books and Book Sections

  1. Oppenheim AV, Willsky AS, and Young IT, Systems and Signals. Vol. ISBN 0-13-809731-3. 1983, Englewood Cliffs, New Jersey: Prentice-Hall. pp. 796.

  2. Suetens P and Young IT, eds. Medical Image Processing. SPIE Image Processing Symposium. Vol. SPIE-593. 1985. pp. 171.

  3. Young IT, et al., Choosing filter parameters for non-linear image filtering, in Pattern Recognition in Practice II, E.S. Gelsema and L.N. Kanal, Editors. 1986, Elsevier Science Publishers: Amsterdam. pp. 5-14.

  4. Young IT, et al., eds. Signal Processing III, Theories and Applications. . 1986, North-Holland: Amsterdam. pp. 1436.

  5. Van Vliet LJ, Young IT, and Beckers ALD, An Edge Detection Model based on Non-linear Laplace Filtering, in Pattern Recognition and Artificial Intelligence, E.S. Gelsema and L.N. Kanal, Editors. 1988, Elsevier Science Publishers: Amsterdam. pp. 63-73.

  6. Young IT and Roos R, Acuity: Image analysis for the personal computer, in Pattern Recognition and Artificial Intelligence, E.S. Gelsema and L.N. Kanal, Editors. 1988, Elsevier Science Publishers: Amsterdam. pp. 5Ð16.

  7. Young IT, Image Fidelity: Characterizing the Imaging Transfer Function, in Fluorescence Microscopy of Living Cells in Culture: Quantitative Fluorescence Microscopy Ð Imaging and Spectroscopy, D.L. Taylor and Y.L. Wang, Editors. 1989, Academic Press: San Diego. pp. 1Ð45.

  8. Van Vliet LJ, et al., Athena: A MacintoshÐBased Interactive Karyotyping System, in Automation of Cytogenetics, C. Lundsteen and J. Piper, Editors. 1989, Springer-Verlag: Berlin. pp. 47-66.

  9. Young IT, Van Vliet LJ, and Mayall BH, Athena: Semi-Automated Karyotyping System, in Advances in Analytical Cellular Pathology, Proceedings of the First Conference of the European Society for Analytical Cellular Pathology, G. Burger, M. Oberholzer, and G.P. Vooijs, Editors. 1991, Excerpta Medica: Amsterdam. pp. 75-76.

  10. Young IT, Gerbrands JJ, and Van Vliet LJ, Fundamentals of Image Processing. Vol. ISBN 90-75691-01-7. 1995, Delft: PH Publications. pp. 110.

  11. Young IT, Calibration: Sampling Density and Spatial Resolution, in Current Protocols in Cytometry, vol. 1, J. P. Robinson, Z. Darzynkiewicz, P. N. Dean, L. G. Dressler, P. S. Rabinovich, C. S. Stewart, H. J. Tanke, and L. L. Wheeless, Eds. New York: John Wiley & Sons, Inc., 1997, pp. 2.6.1-2.6.14.

  12. Van Vliet LJ, D. Sudar D, and Young IT, Digital Fluorescence Imaging Using Cooled Charge-Coupled Device Array Cameras, in Cell Biology: A Laboratory Handbook, vol. 3, J. E. Celis, Ed. London: Academic Press, 1998, pp. 109-120.

  13. Van Vliet LJ, Boddeke FR, Sudar D, and Young IT, Image Detectors for Digital Image Microscopy, in Digital Image Analysis of Microbes, Modern Microbiological Methods, M. H. F. Wilkinson and F. Schut, Eds. Chichester, United Kingdom: John Wiley & Sons, 1998, pp. 37-64.

  14. Young IT, Gerbrands JJ, and van Vliet LJ, Image Processing Fundamentals, in The Digital Signal Processing Handbook, V. K. Madisetti and D. B. Williams, Eds. Boca Raton, Florida: CRC Press in cooperation with IEEE Press, 1998, pp. 51.1 - 51.81.

  15. Ellenberger SE and Young IT, Microscope image acquisition, in Image Processing and Analysis, The Practical Approach Series, R. Baldock and J. Graham, Eds. Oxford: Oxford University Press, 1999, pp. 1-36.

  16. Young, I.T., Shading Correction: Compensation for Illumination and Sensor Inhomogeneities, in Current Protocols in Cytometry, J.P. Robinson, et al., Editors. 2000, John Wiley & Sons, Inc.: New York. p. 2.11.1-2.11.12.

  17. Castleman KR and Young IT, Microscope image acquisition, in Microscope Image Processing, Q. Wu, F.A. Merchant, and K. R. Casteleman, Eds. Academic Press, 2008, pp. 1-25.

  18. Young IT, Where the light was not: Failure in education, 2009, pp. 1-17.



Journals

  1. Young IT and Jovin TM: Editors of Bioimaging, IOP Publishing Co, Bristol, England.
  2. Young IT and Mayall BH, The Solid-State Automated Microscope. Energy and Technology Review, 1982. UCRL-52000-82-1(January): p. 1-9.
  3. Benaron DA, et al., Quantification of Mammalian Sperm by Slit-Scan Flow Cytometry. Cytometry, 1982. 2(5): p. 344-349.
  4. Young IT, et al., Quantitative Analysis of Radiation-Induced Changes in Sperm Morphology. Analytical and Quantitative Cytology, 1982. 4(3): p. 207-216.
  5. Norgren RM, Gray JW, and Young IT, Restoration of Profiles from Slit- Scan Flow Cytometry. IEEE Trans. Biomed. Eng., 1982. BME-29(2): p. 101-106.
  6. Young IT, et al., SSAM: Solid-State Automated Microscope. IEEE Trans. Biomed. Eng., 1982. BME-29(2): p. 70-82.
  7. Young IT, Solid State Automated Microscope, USA, Patent # 4398211, 9 August 1983.
  8. Young IT, Book Review: Image Analysis and Mathematical Morphology. Cytometry, 1983. 4(2): p. 184-185.
  9. King EB, et al., Analytical Studies of Foam Cells from Breast Cancer Precursors. Cytometry, 1984. 5(2): p. 124-130.
  10. Young IT, et al., Morphologic Changes in Rat Urothelial Cells during Carcinogenesis II: Image Cytometry. Cytometry, 1984. 5(5): p. 454-462.
  11. Kaman EJ, et al., Image Processing for Mitoses in Sections of Breast Cancer: A Feasibility Study. Cytometry, 1984. 5(3): p. 244-249.
  12. Groen FCA, Young IT, and Ligthart G, A comparison of different focus functions for use in autofocus algorithms. Cytometry, 1985. 6(2): p. 81-91.
  13. Young IT, Verbeek PW, and Mayall BH, Characterization of chromatin distribution in cell nuclei. Cytometry, 1986. 7: p. 467-474.
  14. Young IT, Sampling density and quantitative microscopy. Analytical and Quantitative Cytology and Histology, 1988. 10(4): p. 269-275.
  15. Groen FCA, et al., Human chromosome classification based on local band descriptors. Pattern Recognition Letters, 1989. 9: p. 211-222.
  16. Van Vliet LJ, Young IT, and Beckers ALD, A Non-linear Laplace Operator as Edge Detector in Noisy Images. Computer Vision, Graphics, and Image Processing, 1989. 45: p. 167-195.
  17. Van Vliet LJ, Young IT, and Mayall BH, The Athena semi-automated karyotyping system. Cytometry, 1990. 11(1): p. 51-58.
  18. Mayall BH, et al., Experience with the Athena semi-automated karyotyping system. Cytometry, 1990. 11(1): p. 59-72.
  19. De Meester U, et al., Towards a Quantitative Grading of Bladder Tumors. Cytometry, 1991. 12(7): p. 602-613.
  20. Verbeek FJ, et al., 3D Base: A geometric data base system for the analysis and visualization of 3D-shapes obtained from parallel serial sections including three different geometric representations. Comp. Med. Imaging & Graphics, 1993. 17(3): p. 151-163.
  21. Starink JP and Young IT, Localization of circular objects. Pattern Recognition Letters, 1993. 14(11): p. 895-905.
  22. Netten H, et al., A fast scanner for fluorescence microscopy using a 2-D CCD and time delayed integration. Bioimaging, 1994. 2(4): p. 184-192.
  23. Boddeke FR, et al., Autofocusing in microscopy based on the OTF and sampling. Bioimaging, 1994. 2(4): p. 193-203.
  24. Young IT and Van Vliet LJ, Recursive Implementation of the Gaussian Filter. Signal Processing, 1995. 44(2): p. 139-151.
  25. Song L, et al., Photobleaching kinetics of fluorescein in quantitative fluorescent microscopy. Biophysical Journal, 1995. 68(June): p. 2588-2600.
  26. Netten H, et al., Fluorescent dot counting in interphase cell nuclei. Bioimaging, 1996. 4(2): p. 93-106.
  27. Young IT, Not just pretty pictures: Digital quantitative microscopy. Proc. RMS, 1996. 31(4): p. 311-313.
  28. Young IT, Quantitative Microscopy. IEEE Engineering in Medicine and Biology, 1996. 15(1): p. 59-66.
  29. Vrolijk H, et al., Automation of spot counting in interphase cytogenetics using brightfield microscopy. Cytometry, 1996. 24(2): p. 158-166.
  30. Netten H, et al., FISH and Chips: Automation of Fluorescent Dot Counting in Interphase Cell Nuclei. Cytometry, 1997. 28(1): p. 1-10.
  31. Schenkeveld VME and Young IT, Simulations of Measurements of Fluorescence Lifetimes Using Noise-Modulated Light, Journal of Fluorescence, vol. 7, pp. 55-58, 1997.
  32. Song L, Van Gijlswijk RPM, Young IT, and Tanke HJ, Influence of fluorochrome labeling density on the photobleaching kinetics of fluorescein in microscopy, Cytometry, vol. 27, pp. 213-223, 1997.
  33. Van den Doel LR, Klein AD, Ellenberger SL, H. Netten H, Boddeke FR, van Vliet LJ, and Young IT, Quantitative evaluation of light microscopes based on image processing techniques, Bioimaging, vol. 6, pp. 138-149, 1998.
  34. Santos A, Young IT. Model-Based Resolution: Applying the Theory in Quantitative Microscopy. Applied Optics 2000;39(17):2948-2958.
  35. Bakker Md, Verbeek PW, Steenvoorden GK, Young IT. The PSD Transfer Function. IEEE Trans. Elec. Dev. 2002;49(1):202-206.
  36. Polder G, Heijden GWAMvd, Young IT. Spectral Image Analysis for Measuring Ripeness of Tomatoes. Transaction of the ASAE 2002;45(4):1155-1161.
  37. Young IT, Vliet LJv, Ginkel Mv. Recursive Gabor Filtering. IEEE Transactions on Signal Processing 2002;50(11):2798-2805.
  38. G. Polder, G.W.A.M. van der Heijden, L.C. Paul Keizer, and I.T. Young, Calibration and characterisation of imaging spectrographs, J. Near Infrared Spectroscopy, vol. 11, no. 3, 2003, 193-210.
  39. G. Polder, G.W.A.M. van der Heijden, and I.T. Young, Tomato sorting using independent component analysis on spectral images, Real-Time Imaging, vol. 9, no. 4, 2003, 253-259.
  40. Guijt-van Duijn RA, Moerman R, Kroon A, Dedem Gv, Doel LRvd, Vliet LJv, Young IT, Laugere F, Bossche A, Sarro PM. Miniaturized analytical assays in biotechnology. Biotechnology Advances 2003;21(5):431-444.
  41. Young IT, Moerman R, Doel LRvd, Iordanov VP, Kroon A, Dietrich HRC, Dedem Gv, Bossche A, Gray BL, Sarro PM and others. Monitoring enzymatic reactions in nanoliter wells. Journal of Microscopy 2003;212(3):254-263.
  42. Dietrich HRC, Knoll J, Doel LR vd, Dedem Gv, Daran-Lapujade P, Vliet LJv, Moerman R, Pronk JT, Young IT. Nanoarrays: A Method for Performing Enzymatic Assays. Anal. Chem. 2004;76(14):4112-4117.
  43. Chuang, TC, Moshir, S, Garini, Y, Chuang, AY, Young, IT, Vermolen, B, Doel, R vd, Mougey, V, Perrin, M, Braun, M, Kerr, PD, Fest, T, Boukamp, P & Mai, S (2004) The three-dimensional organization of telomeres in the nucleus of mammalian cells. BMC Biology 2, 12.
  44. Louis, SF, Vermolen, BJ, Garini, Y, Young, IT, Guffei, A, Lichtensztejn, Z, Kuttler, F, Chuang, TCY, Moshir, S, Mougey, V, Chuang, AYC, Kerr, PD, Fest, T, Boukamp, P & Mai, S (2005) c-Myc induces chromosomal rearrangements through telomere and chromosome remodeling in the interphase nucleus. Proceedings of the National Academy of Sciences USA 102, 9613-9618.
  45. Polder, G, Heijden, GWAM vd, Voet, H vd & Young, IT (2004) Measuring surface distribution of carotenes and chlorophyll in ripening tomatoes using image spectrometry. Postharvest Biology and Technology 34, 117-129.
  46. G. Polder, G.W.A.M. van der Heijden, L.C. Paul Keizer, and I.T. Young, Calibration and characterisation of imaging spectrographs, J. Near Infrared Spectroscopy, vol. 11, no. 3, 2003, 193-210.
  47. G. Polder, G.W.A.M. van der Heijden, and I.T. Young, Tomato sorting using independent component analysis on spectral images, Real-Time Imaging, vol. 9, no. 4, 2003, 253-259.
  48. B.J. Vermolen, Y. Garini, and I.T. Young, 3D Restoration with multiple images acquired by a modified conventional microscope, Microscopy Research and Technique, vol. 64, no. 2, 2004, 113-125.
  49. Y. Garini, B.J. Vermolen, and I.T. Young, From micro to nano: recent advances in high-resolution microscopy, Current Opinion in Biotechnology, vol. 16, no. 1, 2005, 3-12.
  50. M. Fulwyler, Q.S. Hanley, C. Schnetter, I.T. Young, E.A. Jares-Erijman, D.J. Arndt-Jovin, and T.M. Jovin, Selective Photoreactions in a Programmable Array Microscope (PAM): Photoinitiated Polymerization, Photodecaging, and Photochromic Conversion, Cytometry, vol. 67A, no. 2, 2005, 68-75.
  51. G.O.F. Parikesit, A.P. Markesteijn, V.G. Kutchoukov, O. Piciu, A. Bossche, J. Westerweel, Y. Garini, and I.T. Young, Electroosmotic flow analysis of a branched U-turn nanofluidic device, Lab on a Chip, vol. 5, no. 10, 2005, 1067-1074.
  52. V. Raz, F. Carlotti, B.J. Vermolen, E. van der Poel, W.C.R. Sloos, S. Knaan-Shanzer, A.A.F. de Vries, R.C. Hoeben, I.T. Young, H.J. Tanke, Y. Garini, and R.W. Dirks, Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells, Journal of Cell Science, vol. 119, no. 20, 2006, 4247-4256.
  53. Y. Garini, I.T. Young, and G. McNamara, Spectral Imaging: Principles and Applications, Cytometry Part A, vol. 69A, no. 8, 2006, 735-747.
  54. M.W. Docter, I.T. Young, O.M. Piciu, A. Bossche, P.F.A. Alkemade, P.M. van den Berg, and Y. Garini, Measuring the wavelength-dependent divergence of transmission through sub-wavelength hole-arrays by spectral imaging, Optics Express, vol. 14, no. 20, 2006, 9477-9482.
  55. I.T. Young, Y. Garini, B.J. Vermolen, G.F. Liqui Lung, G. Brouwer, S. Hendrichs, J. Spoelstra, E. Wilhelm, M. Zaal, and M. el Morabit, Absolute fluorescence calibration, European Journal of Medical Genetics, vol. 48, no. 4, 2005, 533-533.
  56. M.W. Docter, P.M. van den Berg, P.F.A. Alkemade, V.G. Kutchoukov, O.A. Piciu, A. Bossche, I.T. Young, Y. Garini, Structured illumination microscopy using extraordinary transmission through sub-wavelength hole-arrays, Journal of Nanophotonics, vol 1, 011665, 10 pages, 2007.
  57. V. Raz, B.J. Vermolen, I.T. Young, R.W. Dirks, Y. Garini, Similar spatial reorganization of lamina, telomeres and centromeres in senescent and apoptotic human mesenchymal stem cells, Chromosome research, 15, 2007.
  58. G.O.F. Parikesit, A.P. Markesteijn, O.M. Piciu, A. Bossche, J. Westerweel, I.T. Young, Y. Garini, Size-dependent trajectories of DNA macromolecules due to insulative dielectrophoresis in submicrometer-deep fluidic channels, Biomicrofluidics 2, 024103, 2008.
  59. Dietrich, H. R. C., B. Vermolen, et al. (2007). "A New Optical Method for Characterizing Single Molecule Interactions based on Dark Field Microscopy." SPIE: Ultrasensitive and Single-Molecule Detection Technologies II 6444: 1-8.
  60. Docter, M. W., P. v. d. Berg, et al. (2007 ). "Structured illumination microscopy using extraordinary transmission through sub-wavelength hole-arrays." J. Nanophotonics 1(011665): 1-10.
  61. Raz, V., B. Vermolen, et al. (2008). "The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells." J. Cell. Sci. 121: 4018-4028.
  62. Vermolen, B. J., Y. Garini, et al. (2008). "Segmentation and analysis of the three-dimensional redistribution of nuclear components in human mesenchymal stem cells." Cytometry 73A(9): 816-824.
  63. Brinkers, S., H. R. C. Dietrich, et al. (2009). "The persistence length of double stranded DNA determined using dark field tethered particle motion." J. Chemical Physics 130(215195): 1-9.
  64. Dietrich, H. R. C., B. Rieger, et al. (2009). "Tethered particle motion mediated by scattering from gold nanoparticles and darkfield microscopy." J. Nanophotonics 3(031795): 1-17.
  65. Zhao, Q., I. T. Young, et al. (2011). "Photon budget analysis for fluorescence lifetime imaging microscopy." J. Biomedical Optics 16(8): 15.
  66. Lindner, M., et al., Studies of single molecules in their natural form. Israel Journal of Chemistry, 2009. 49(3-4): p. 283-291.
  67. Righolt, C.H., et al., Translocation frequencies and chromosomal proximities for selected mouse chromosomes in primary B lymphocytes. Cytometry Part A, 2011. 79 A(4): p. 276-283.



Conference proceedings

  1. Young IT. The Use of Digital Image Processing Techniques for the Calibration of Quantitative Microscopes. in Applications of Digital Image Processing. 1983: SPIE, SPIE-397, p. 326-335.

  2. Beckers ALD, Dorst L, and Young IT. The Choice of Filter Parameters for Non-Linear Grey-Value Image Processing. in Architectures and Algorithms for Digital Image Processing. 1985. Cannes, France, SPIE-596, p. 120-128.

  3. Coemet-Penning MJ, Woerlee M, and Young IT. Dynamic Characteristics of the Human Heart Rate. in EUSIPCO-86. 1986. The Hague, The Netherlands: North Holland, p. 1389-1392.

  4. Young IT, Orange CM, and Mullikin JC. An evaluation of commercial architectures for three-dimensional image analysis. in Proceedings of the workshop on parallel processing. 1990. Bhabha Atomic Research Center, Bombay, India, p. IP1-IP13.

  5. Van Vliet LJ and Young IT. ICAS: Scanner and Analyzer for Fluorescent Microscopy. in XIV International Meeting of the Society for Analytical Cytology. 1990. Asheville, North Carolina: Wiley-Liss, Cytometry - Supplement 4, p. 5.

  6. Song L, et al. Texture Analysis for Characterization of Chromatin Distribution in Breast Cancer Prognosis. in XV Congress of the International Society for Analytical Cytology. 1991. Bergen, Norway: Wiley-Liss, Cytometry, Supplement 5, p. 125.

  7. Young IT, et al. The Quantitative Grading of Bladder Tumors. in XV Congress of the International Society for Analytical Cytology. 1991. Bergen, Norway: Wiley-Liss, Cytometry, Supplement 5, p. 126.

  8. Strasters KC, et al. 3D Texture Analysis of the Chromatin Distribution in Cell Nuclei of Crepis Capillaris. in XV Congress of the International Society for Analytical Cytology. 1991. Bergen, Norway: Wiley-Liss, Cytometry, Supplement 5, p. 122.

  9. Young IT. The Representation of Fluorescent Colors. in The Role of In Situ Hybridization in Automated Cytogenetics. 1991. Leiden, The Netherlands: Boerhaave Committee Leiden, p. 83-88.

  10. Vossepoel AM, et al. Length, Area, and Integrated Optical Density Compared as Features for Chromosome Classification. in XV Congress of the International Society for Analytical Cytology. 1991. Bergen, Norway: Wiley-Liss, Cytometry, Supplement 5, p. 40.

  11. Young IT. Size Calibration in Quantitative Microscopy. in XV Congress of the International Society for Analytical Cytology. 1991. Bergen, Norway: Wiley-Liss, Cytometry, Supplement 5, p. 40.

  12. Netten H, et al. ICAS: Scanner and Analyzer for Fluorescence Microscopy. in XV Congress of the International Society for Analytical Cytology. 1991. Bergen, Norway: Wiley-Liss, Cytometry, Supplement 5, p. 70.

  13. Mullikin JC, Van Driel R, and Young IT. Three-Dimensional Image Analysis Techniques for Determining Organization in Interphase Cell Nuclei. in XV Congress of the International Society for Analytical Cytology. 1991. Bergen, Norway: Wiley-Liss, Cytometry, Supplement 5, p. 121.

  14. Van Vliet LJ, et al. Autofocusing in Fluorescence Microscopy. in XV Congress of the International Society for Analytical Cytology. 1991. Bergen, Norway: Wiley-Liss, Cytometry, Supplement 5, p. 70.

  15. Young IT. Three-dimensional image analysis. in Volume Image Processing - 93. 1993. Utrecht, The Netherlands, p. 35-38.

  16. Young IT. Computer methods in image analysis and pattern recognition. in Microrama. 1993. Pisa, p. 103-105.

  17. Young IT, et al. Depth-of-focus in microscopy. in 8th Scandinavian Conference on Image Analysis. 1993. Troms¿, Norway: Norwegian Society for Image Processing and Pattern Recognition, 1, p. 493-498.

  18. Young IT. Image analysis and pattern recognition in microscopy. in Microrama. 1993. Pisa, p. 19-21.

  19. Netten H, et al., Automation of FISH Dot Counting in Cell Nuclei,, in Third Conference of the European Society for Analytical Cellular Pathology, G. Brugal, Editor. 1994, Elsevier: Grenoble, France. p. 199.

  20. Young IT, et al. Characterization of a color CCD camera. in Microscope Instrumentation. 1994. San Miniato, Italy: Institute of Biophysics CNR, Pisa, Italy, p. 97-92.

  21. Mullikin JC, et al. Methods for CCD Camera Characterization. in SPIE Conference on Image Acquisition and Scientific Imaging Systems. 1994. San Jose, California: SPIE, TC-2173, p. 73-84.

  22. Netten H, et al. Automation of Fluorescent Dot Counting in Cell Nuclei. in 12th IAPR International Conference on Pattern Recognition. 1994. Jerusalem, Israel: IEEE Computer Society Press, Vol. I, p. 84-87.

  23. Netten H, et al., Automation of Fluorescent Dot Counting in Cell Nuclei, in XVII Congress of the International Society for Analytical Cytology. 1994, Wiley-Liss: Lake Placid, New York. p. 13.

  24. Netten H, et al. Integrated microscope system for FISH spot counting. in Microscope Instrumentation. 1994. San Miniato, Italy: Institute of Biophysics CNR, Pisa, Italy, p. 57-58.

  25. Boddeke FR and Young IT. Intensified Camera Systems. in Microscope Instrumentation. 1994. San Miniato, Italy: Institute of Biophysics CNR, Pisa, Italy, p. 29-30.

  26. Young IT. Generalized Convolutional Filters. in 1996 CERN School of Computing. 1996. Egmond aan Zee, The Netherlands: CERN, p. 51-65.

  27. Young IT. Choosing the sampling density. in ASCI'96: 2nd Annual Conf. of the Advanced School for Computing and Imaging. 1996. Lommel, Belgium, p. 236-241.

  28. Young IT. Sampling density for image analysis. in ICPR13: 13th International Conference on Pattern Recognition. 1996. Vienna, Austria: IEEE Computer Society Press, 2, Track B, p. 840-843.

  29. Dijk J, de Ridder D, Verbeek PW, Walraven J, Young IT and van Vliet, LJ (1999) A new measure for the effect of sharpening and smoothing filters on images, SCIA'99 - 11th Scandinavian Conference on Image Analysis (ed. by B. K. Ersboll and P. Johansen) Kangerlussuaq, Greenland, Vol. 1, pp. 213-220. Pattern Recognition Society of Denmark.

  30. Van den Doel LR, Vellekoop ME, Sarro PM, Picioreanu S, Moerman R, Frank J, van Dedem G, Hjelt KT, van Vliet LJ and Young IT (1999) Fluorescence Detection in (sub-)nanoliter microarrays, Micro- and Nanofabricated Structures and Devices for Biomedical and Environmental Applications II (ed. by M. Ferrari) San Jose, California, Vol. 3606, pp. 28-39. SPIE - The International Society for Optical Engineering.

  31. Klein AD, van den Doel LR, Young IT, Ellenberger S and Van Vliet LJ (1998) Quantitative evaluation and comparison of light microscopes, SPIE Conference on Optical Investigation of Cells In Vitro and In Vivo (ed. by D. L. Farkas, R. C. Leif and B. J. Tromberg) San Jose, California, Vol. 3260, pp. 162-173. SPIE - The International Society for Optical Engineering.

  32. Van Vliet LJ, Young IT and Verbeek PW (1998) Recursive Gaussian Derivative Filters, 14th International Conference on Pattern Recognition (ed. by A. K. Jain, S. Venkatesh and B. C. Lovell) Brisbane, Australia, Vol. I, pp. 509-514. IEEE Computer Society Press.

  33. Lohner S, Young IT, Ellenberger SL and de Bakker M (1999) Image distortion in conventional and confocal microscopy, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing VI (ed. by D. Cabib, C. J. Cogswell, J.-A. Conchello, J. M. Lerner and T. Wilson) San Jose, California, Vol. 3605, pp. 129-139. SPIE - The International Society for Optical Engineering.

  34. Moerman R, van den Doel LR, Picioreanu S, Frank J, Marijnissen JCM, van Dedem G, Hjelt KT, Vellekoop ME, Sarro PM and Young IT (1999) Micro-injection of b-D-glucose standards and Amplex red reagent in micro-arrays, Micro- and Nanofabricated Structures and Devices for Biomedical and Environmental Applications II (ed. by M. Ferrari) San Jose, California, Vol. 3606, pp. 119-128. SPIE - The International Society for Optical Engineering.

  35. Ahluwalia, A.K., Jonker, P.P. & Young, I.T. (2000) An Interactive Image Processing Course for the Web First International Conference on Image and Graphics (ed. by Y.-J. Zhang) Tianjin, China, Vol. 5 (Supp.), pp. 589-593. Journal of Image and Graphics.

  36. Doel, L.R.v.d., Vellekoop, M.J., Sarro, P.M., Moerman, R., Frank, J., Dedem, G.v., Hjelt, K.T., Vliet, L.J.v. & Young, I.T. (2000) Microarrays for Biotechnology: The Imaging Challenge First International Conference on Image and Graphics (ed. by Y.-J. Zhang) Tianjin, China, Vol. 5 (Supp.), pp. 36-41. Journal of Image and Graphics.

  37. Doel, L.R.v.d., Vliet, L.J.v., Hjelt, K.T., Vellekoop, M.J., Gromball, F., Korvink, J.G. & Young, I.T. (2000) Nanometer-scale height measurements in micro-machined picoliter vials based on interference fringe analysis 15th ICPR (ed. by A. Sanfeliu, J. J. Villanueva, M. Vanrellet al) Barcelona Spain, Vol. 3, pp. 57-62. IEEE Computer Society.

  38. Young, I.T., Vliet, L.J.v. & Ginkel, M.v. (2000) Recursive Gabor Filtering First International Conference on Image and Graphics (ed. by Y.-J. Zhang) Tianjin, China, Vol. 5 (Supp.), pp. 232-235. Journal of Image and Graphics.

  39. Young, I.T., Hjelt, K.T., Doel, L.R.v.d., Vellekoop, M.J. & Vliet, L.J.v. (2001) Measuring Liquid Volumes in Subnanoliter Wells Biomedical Instrumentation Based on Micro- and Nanotechnology II (ed. by R. P. Mariella and D. V. Nicolau) San Jose, California, Vol. 4265, pp. 75-80. SPIE.

  40. Doel, L.R.v.d., Moerman, R., Dedem, G.v., Young, I.T. & Vliet, L.J.v. (2002) Monitoring Enzyme-catalyzed Reactions in Micromachined Nanoliter Wells using a Conventional Microscope based Microarray Reader Novel Micro- and Nanotechnologies for Bioengineering Applications, Photonics West, BIOS 2002 (ed. by R. P. Mariella and C. J. Murphy) San Jose, California, Vol. 4626, pp. 366-377. SPIE.

  41. Young, I.T., Garini, Y., Dietrich, H.R.C., Oel, W.v. & LiquiÊLung, G. (2004) LEDs for Fluorescence Microscopy Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XI (ed. by J.-A. Conchello, C. Cogswell and T. Wilson) San Jose, California, Vol. 5324, pp. 208-215. SPIE.

  42. Y. Garini, V.G. Kutchoukov, A. Bossche, P.F.A. Alkemade, M.W. Docter, P.W. Verbeek, L.J. van Vliet, and I.T. Young, Toward the development of a three-dimensional midfield microscope, in: Tuan Vo-Dinh, Z. Gryczynski, J.R. Lakowicz (eds.), Plasmonics in Biology and Medicine, Proc. BiOS 2004 (January 24-29, San Jose, CA), Proc. SPIE, vol. 5327, 2004, 115-122.

  43. H.R.C. Dietrich, I.T. Young, and Y. Garini, Advances in the Development of a Novel Method to be used in Proteomics using Gold Nanobeads, in: J. Enderlein, Z.K. Gryczynski (eds.), Ultrasensitive and Single-Molecule Detection Technologies (Proc. Photonics West 2006: Biomedical Optics (BiOS), San Jose, CA, USA, Jan. 21-26), Proc. SPIE, vol. 6092, 2006, 0C/1-8.

  44. M.W. Docter, I.T. Young, O. Piciu, A. Bossche, P.F.A. Alkemade, P.M. van den Berg, and Y. Garini, Measuring the near-field of extraordinary transmission through a periodic hole-array, in: D.L. Andrews, J.-M. Nunzi, A. Ostendorf (eds.), Nanophotonics, Proc. Photonics Europe 2006 (Strasbourg, France, Apr.3-7), Proc. SPIE, vol. 6195, 2006, 1L/1-8.

  45. I.T. Young, Y. Garini, B. Vermolen, G. Liqui Lung, G. Brouwer, S. Hendrichs, M. el Morabit, J. Spoelstra, E. Wilhelm, and M. Zaal, Absolute Fluorescence Calibration - Invited Paper, in: D.L. Farkas, D.V. Nicolau, R.C. Leif (eds.), Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues IV (Proc. Photonics West 2006: Biomedical Optics (BiOS), San Jose, CA, USA, Jan. 21-26), Proc. SPIE, vol. 6088, 2006, 0U/1-9.

  46. H.R.C. Dietrich, B.J. Vermolen, B. Rieger, I.T. Young, Y. Garini, Y, A New Optical Method for Characterizing Single Molecule, Proceedings SPIE, 6444E, 2007.

  47. G.O.F. Parikesit, Y. Garini, I.T. Young, A branched U-turn nanofluidic device for continuous sorting of macromolecules, 3rd International Symp. on Separation and Characterization of Natural and Synthetic Macromolecules, 2007, 86.
  48. G.O.F. Parikesit, A.P. Markensteijn, J. Westerweel, I.T. Young, Y. Garini, Free Flow Dielectrophoresis - A numerical Study, Proceedings of uTAS (Miniaturized Systems for Chemistry and Life Sciences, 2007, 221-223.
  49. S. Brinkers, H.R.C. Dietrich, B.Rieger, I. Ted Young, Detection of DNA hybridization events using the diffusion constant in TPM experiments, Focus on Microscopy, Valencia, Spain, April 10-13, 2007

  50. H.R.C. Dietrich, F.G.M. Wiertz, B.J. Vermolen, B. Rieger, H.A. Heering, I.T. Young and Y. Garini, The Detection of DNA-protein interactions under near-native biological conditions,13th International Workshop on "Single Molecule Spectrocopy and Ultrasensitive Analysis in the Life Sciences", Berlin, Germany, September 19-21, 2007
  51. H.R.C. Dietrich, F.G.M. Wiertz, B.J. Vermolen, B. Rieger, H.A. Heering, I.T. Young and Y. Garini, The Detection of DNA-protein interactions under near-native biological conditions,Annual Dutch Meeting on Molecular and Cellualar Biophysics, Veldhoven, The Netherlands, October 1-2, 2007



PhD Theses Supervised in The Netherlands

  1. Dorst L:  Discrete Straight Line Segments: Parameters, Primitives and Properties. Delft University of Technology, 1986.

  2. Komen ER:  Low-level Image Processing Architectures. Delft University of Technology, 1990.

  3. Vrooman HA:  Quantitative analysis of interferograms. Delft University of Technology, 1991.

  4. Verwer BJH:  Distance transforms, metrics, algorithms, and applications. Delft University of Technology, 1991.

  5. Jonker PP:  Morphological Image Processing: Architecture and VLSI Design. Delft University of Technology, 1992.

  6. Van Vliet LJ:  Grey-scale measurements in multi-dimensional digitized images. Delft University of Technology, 1993.

  7. Mullikin JC:  Discrete and continuous methods for three-dimensional image analysis. Delft University of Technology, 1993.

  8. Kraaijveld MA:  Small sample behavior of multi-layer feedforward network classifiers: theoretical and practical aspects. Delft University of Technology, 1993.

  9. Buurman J:  Object recognition for flexible assembly using stereo vision. Delft University of Technology, 1993.

  10. Schmidt WF:  Neural pattern classifying systems. Delft University of Technology, 1994.

  11. Strasters KC:  Quantitative Analysis in Confocal Image Cytometry. Delft University of Technology, 1994.

  12. Orange C:  Supervised Boundary Formation. Delft University of Technology, 1994.

  13. Janssen DT:  The Application of Model-Based Image Processing to the Interpretation of Maps. Delft University of Technology, 1995

  14. Frietman EEE:  Opto-Electronic Processing & Networking: A Design Study. Delft University of Technology, 1995

  15. Van der Heijden GWAM:  Applications of Image Analysis in Plant Variety Testing. Delft University of Technology, 1995

  16. Verbeek FJ:  Three-Dimensional Reconstruction of Biological Sections Including Deformation Correction. Delft University of Technology, 1995

  17. Song L:  Photobleaching Kinetics of Fluorescein in Quantitative Fluorescence Microscopy. University of Leiden, 1996

  18. Netten H:  Automated Image Analysis of FISH-Stained Cell Nuclei. Delft University of Technology, 1997

  19. Schenkeveld E:  Measurement of Fluorescence Lifetimes using Noise and PRBS Modulated Light. Delft University of Technology, 1998

  20. Hoekstra A:  Generalisation of Feed Forward Neural Classifiers. Delft University of Technology, 1998

  21. Verveer PJ:  Computational and Optical Methods for Improving Resolution and Signal Quality in Fluorescence Microscopy. Delft University of Technology, 1998

  22. Van Kempen GMP:  Image Restoration in Fluorescence Microscopy. Delft University of Technology, 1999

  23. Boddeke F:  Quantitative Fluorescence Microscopy. Delft University of Technology, 1999

  24. de Bakker M:  The PSD Chip: High speed acquisition of range images. Delft University of Technology, 2000

  25. Ellenberger SL:  Influence of defocus on measurements in microscope images. Delft University of Technology, 2000

  26. Fens TW:  Petrophysical Properties from small rock samples using Image Analysis techniques. Delft University of Technology, 2000

  27. Tax DMJ:  One-class classification. Delft University of Technology, 2001

  28. Olk JGE:  Distributed bucket processing. Delft University of Technology, 2001

  29. Skurichina M:  Stabilizing weak classifiers. Delft University of Technology, 2001

  30. Van den Doel LR:  Quantitative Microscopic Techniques for Monitoring Dynamic Processes in Microarrays. Delft University of Technology, 2002

  31. Van Ginkel M:  Image Analysis using Orientation Space based on Steerable Filters. Delft University of Technology, 2002

  32. Soviany C:  Embedding Data and Task Parallelism in Image Processing Applications. Delft University of Technology, 2003

  33. Cremer F:  Polarimetric infrared and sensor fusion for the detection of landmines. Delft University of Technology, 2003

  34. Dijk J:  In search of an Objective Measure for the Perceptual Quality of Printed Images. Delft University of Technology, 2004

  35. Epstein A:  Parallel Hardware Architectures for the Life Sciences. Delft University of Technology, 2004

  36. Polder G:  Spectral imaging for measuring biochemicals in plant material. Delft University of Technology, 2004

  37. Han J:  Fault-tolerant architectures for nanoelectronic and quantum devices. Delft University of Technology, 2004

  38. Pekalska E:  Dissimilarity representations in pattern recognition: Concepts, theory, and applications. Delft University of Technology, 2005

  39. Persa S-F:  Sensor fusion in head pose tracking for augmented reality. Delft University of Technology, 2006

  40. Suprijanto:  Image processing for monitoring locally induced hyperthermia with magnetic resonance imaging. Delft University of Technology, 2006

  41. Perikesit GOF: Nanofluidic electrokinetics in quasi-two-dimensional branched U-turn channels. Delft University of Technology, 2008

  42. Docter MW: Midfield microscope: exploring the extraordinary. Delft University of Technology, 2008

  43. Vermolen BJ: Nuclear Architecture: Image Processing and Analysis. Delft University of Technology, 2009

  44. Dietrich HRC: Nanoassays for Biomolecular Research. Delft University of Technology, 2009

  45. Brinkers S: All that glitters is gold, nucleic acid detection using tethered gold. Delft University of Technology, 2011

  46. Zhao Q: A Solid-State Camera System for Fluorescence Lifetime Microscopy. Delft University of Technology, 2014


For further information or reprint requests, please contact me (e-mail preferred).


e-mail: i.t.young at tudelft dot nl
Last update: Thursday, 6 March 2014